A Acute promyelocytic leukemia [Ref. Harrison 16'11/e p 636] Disseminated intravascular coagulation is associated with promyelocytic leukemia Acute promyelocytic leukemia (AML-M3) constitutes 5-10% of all cases of AML The leukemic cells of these type of anemia are hypergranular. Granules of these leukemic cells (promyelocytes) contain thromboplastin like material resulting in widespread disseminated intravascular coagulation. Also know Majority of M₂ cases demonstrate a reciprocal translocation involving chromosome 15 and 17, t (15; 17)
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A resourceful channel dedicated to pathology, offering a rich collection of educational videos and books. Engage with detailed discussions on various pathological conditions, medical insights, and recent research findings, all presented in an informative and accessible tone.
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